Researchers from Johns Hopkins Medicine examined six adults and found evidence that a single vaping session of cannabis with a chemical makeup that was similar to hemp products legally sold in the market could possibly result in positive urine drug screening tests, which are commonly administered by employers and criminal justice America is one of the world’s leading economies. Any crop of cannabis that has 0.3% or less THC in dry weight is considered hemp according to the government. The substance delta-9-tetrahydrocannabinol (THC) in cannabis is what is responsible for granting the high and producing the subjective and cognitive effects typically associated with marijuana. U.S. economic report for 2018 is out, and it can be found here In the wake of the Farm Bill, hemp has been legalized for production and sale, and a variety of hemp products, such as oils, vaping cartridges and hemp flowers for smoking, can now be legally purchased through specialty stores, general retail stores and websites across the country. There are now more and more applications for hemp in medicine and the wellness market, particularly when it comes to its component CBD, short for cannabidiol, one of the more than 100 cannabinoids found in cannabis plants. 

 

Approximately $600 million to $2 billion in CBD sales were recorded in the last year, according to Cowen & Co., a New York-based investment bank. In spite of its size and success, this industry is still Published in the November issue of the journal, Researchers reported that, in a study published on Page 4 of the Journal of Analytical Toxicology, two out of six study participants tested positive for THC after vaping cannabis that contained 0.39 percent THC using urine testing methods that are typically used for employment or criminal justice In spite of the fact that the cannabis used in this study does not meet the federal definition of hemp, it has a THC concentration of 0.39 %, which is just 0.09 % more than the legal limit. Legal hemp products are rarely used for medical purposes once, as in this study, and prior studies have shown that THC and its metabolites can accumulate over time, says Johns Hopkins Bayview Medical Center postdoctoral fellow Tory Spindle, Ph.D. I do not believe anyone has ever not used CBD products at least once. Yet the majority of users are completely unaware of the possibility of getting high or being tested for drugs if the product they use is contaminated with THC.” states CBD has been demonstrated to be an effective treatment for two rare forms of epilepsy in children, but there is not enough evidence to support the use of CBD for any other health reason, according to the U.S. FDA. This agency regulates food and drugs. Although CBD products are extremely diverse, consumers and suppliers alike claim that CBD has benefits for everything from anxiety to insomnia to general well-being. Hemp oil/tinctures, food items (such as gummy bears), vape pens similar to electronic cigarettes, and creams, patches, balms, and gels that can be applied topically to the skin can all be used to administer CBD. Three women and three men, the average age of each was 31 years old, were recruited for the current study. A participant self-identified as African American in this study, while the remaining participants described themselves as white. A batch of cannabis used in this study contained 10.5% CBD and 0.39% THC, a ratio of CBD to THC that is comparable to that found in legal hemp Participants in the trial consumed between a little less than 1 gram and a little more than 4 grams of cannabis, which contained The cannabis vapor was collected into a balloon and inhaled by participants who had heated the cannabis. Furthermore to vaping the CBD/THC cannabis, study participants were also given pure CBD in a capsule, vaporized pure CBD and placebo (a mock CBD pill and vaporized cannabis that was stripped of CBD and THC) during another three dosing sessions one week apart. CBD was delivered in 100 milligram doses per session in all active drug conditions (excluding placebo).

The message is that people should be mindful of single dose or cumulative THC exposure, and that these products may cause an unexpected positive drug test result. Since the market for CBD products is so young and its popularity is growing so rapidly, we want to make them aware that their drugs may show up positive.

There were two participants who tested positive for THCCOOH among the six who vaped the low-THC/high-CBD cannabis. In the other sessions of the test (pure CBD capsules, pure CBD vape or placebo), no positive urine drug test results were observed. Based on these results, Vandrey suggests that finding pure CBD, when used once by itself, will not lead to a positive drug test. The researchers note that some people test positive for THC even if they have had little exposure to the substance. There may be individual differences in drug metabolism or puffing behaviors, such as inhalation depth, and that may affect the breakdown or buildup of cannabinoids in the body. According to the team, in addition to repeating their studies using products that fall within the current federal hemp regulations regarding THC content, they also intend to examine the impact of repeated CBD/hemp exposure on drug test results. Besides Edward Cone and George Bigelow of Johns Hopkins, David Kuntz of Clinical Reference Laboratory, John Mitchell of RTI International, and Ronald Flegel of the Substance Abuse and Mental Health Services Administration (SAMHSA), the study was also co-authored by these authors. SAMHSA and the National Institute on Drug Abuse contributed funding for this study (T32DA07202). The COI is Zynerba Pharmaceuticals, FSD Pharma and Canopy Health Innovations Inc. have paid Vandrey consulting fees or provided honoraria to him. There are now more and more applications for hemp in medicine and the wellness market, particularly when it comes to its component CBD, short for cannabidiol, one of the more than 100 cannabinoids found in cannabis plants. As reported by the New York-based investment bank Cowen & Co., CBD sales in the last year ranged between $600 million and $2 billion. The booming niche continues to be largely unregulated in spite of its size. A Nov. 2014 article detailed the findings of a new study. The researchers report on page 4 in the Journal of Analytical Toxicology that two out of six study participants tested positive after vaporizing cannabis containing 0.39% THC using urine testing methods that conform to the type of testing typically performed for employment or criminal justice-related Despite the fact that the cannabis used in this study does not currently comply with the federal definition of hemp, there was just a 0.09 percent excess of THC over federal regulations.

Researchers say that people who use legal hemp products for medical purposes rarely use them just once as we did in our study. Previous research shows that THC and its metabolites accumulate over time, says postdoctoral fellow Dr. Tory Spindle It’s hard to find anyone who has not used a CBD product at least once, says Vandrey, but most are unaware of the possibility that using these products could result in THC exposure or a positive drug test. The U.S. Food and Drug Administration says there are currently insufficient data to support use of CBD for any other health condition. CBD is an effective treatment for two rare forms of pediatric epilepsy, but there is still insufficient evidence to support its use for any other health condition. There is a food and drug administration. Although CBD products are extremely diverse, consumers and suppliers alike claim that CBD has benefits for everything from anxiety to insomnia to general well-being. A CBD product can be swallowed as an oil or tincture, eaten in food form (e.g., gummies), inhaled using vape pens similar to electronic cigarettes or applied topically to the skin as a cream, gel, balm or patch. The researchers recruited three women and three men of an average age of 31 years old to participate in the current study. There was only one African American participant and the rest were white. The batch of cannabis used in this particular study contained 10.5% CBD and 0.39% THC, a 26 to 1 ratio of CBD to THC similar to that often found in legal hemp and CBD Study participants vaporized approximately one gram of cannabis, which contained 3.7 milligrams of THC and 100 milligrams of CBD. The cannabis vapor was collected into a balloon and inhaled by participants who had heated the cannabis. A few weeks after the study volunteers were given the high CBD/low THC cannabis, they also received pure CBD in capsule form, vaporized pure CBD, and a placebo (a mock CBD pill and vaporized cannabis with CBD removed) at three additional dosing sessions one week later. A 100 milligram dose of CBD was administered every session in all active drug conditions (excluding placebo). During this study, researchers used an on-site dipstick test to determine whether someone had used cannabis, and a more sensitive test method to confirm a positive result at a concentration of 15 nanograms per milliliter of THCCOOH. It means that people should be cautious of single-dose or cumulative THC exposure and know that these now legal products may cause unexpected positive drug test results. Since CBD products are so new and their popularity is expanding so rapidly, we want the public to know that a positive test result

The THCCOOH was detected in the urine of two out of six participants who vaped the cannabis with low THC and high CBD. In the other sessions of the test (pure CBD capsules, pure CBD vape or placebo), no positive urine drug test results were observed. According to Vandrey, an individual using pure CBD once will not be affected by a positive drug test once its used alone. According to Spindle, it may not take much exposure to THC to trigger a positive blood test for some people. There may be variation in drug metabolism and puffing behaviors such as inhalation depth that could affect cannabinoids buildup in the body, the researchers suggest. It is planned that they will repeat their studies on products that fall within the current federal hemp regulations with respect to THC content and will also study the effect of repeated CBD exposure on drug test results. In addition to Cone and Bigelow, David Kuntz of Clinical Reference Laboratory, John Mitchell of RTI International, and Ronald Flegel of the Substance Abuse and Mental Health Services Administration (SAMHSA) also contributed to the study. The research for this article was supported by SAMHSA and the National Institute on Drug Abuse (T32DA07202).